Congenital Hypothyroidism in Neonates of a Tertiary Care Hospital

Ahmad, Adeel and Wasim, Anam and Hussain, Shahida and Saeed, Muhammad and Ahmad, Bilal Munir and Rehman, Khalil ur (2017) Congenital Hypothyroidism in Neonates of a Tertiary Care Hospital. Pakistan Journal of Medical Sciences, 33 (5). ISSN 1681-715X

[thumbnail of 12986-60562-1-PB.pdf] Text
12986-60562-1-PB.pdf - Published Version

Download (323kB)

Abstract

Objective: To determine neonatal congenital hypothyroidism among neonates born in a tertiary care hospital of Lahore Pakistan.

Methods: This cross-sectional study was carried out at Pathology Department of Allama Iqbal Medical College, Lahore in collaboration with Pediatrics and Gynecology & Obstetrics Department, Jinnah Hospital, Lahore Pakistan. A total of 770 babies were included in this study, both male and female. About 2 ml venous blood samples were collected aseptically from the neonates in sterile clotted tube. Serum was separated and serum TSH was determined by ELISA method.

Results: Out of total 770 neonates, 48.9% were female and 51.0% were males with the ratio of 1:1.04. Neonatal congenital hypothyroidisim (TSH, >30 mIU/L), was observed in 0.4% (Frequency, 1:257) nenates, with the incidence rate of 1:257. Female to male ratio of hypothyroid neonates was 2:1. The mode of delivery vise distribution showed, among n=251 neonates born by normal delivery, only a single case of hypothyroidism was detected, and among n=519 neonates delivered by cesarean section, only two neonates were belong to hypothyroidism.

Conclusion: The frequency of Congenital Hypothyroidism is notably higher in pediatric community than reported in most other countries. This result emphasizes the necessity of a nationwide screening program.

Item Type: Article
Subjects: Impact Archive > Medical Science
Depositing User: Managing Editor
Date Deposited: 28 Apr 2023 04:25
Last Modified: 11 Jan 2024 04:03
URI: http://research.sdpublishers.net/id/eprint/2137

Actions (login required)

View Item
View Item