Xanthogranulomatous Cholecystitis - An Uncommon Variant

Aim: Xanthogranulomatous cholecystitis is a rare variant of inflammatory disease of gallbladder which is marked by the presence of lipid-laden macrophages along with extensive fibrosis. It is frequently confused with carcinoma of the gallbladder preoperatively on imaging or on gross appearance intraoperatively. Definitive diagnosis is confirmed on histopathological examination. Imaging may shed light on this condition preoperatively but may a time this may present as a histological surprise. Accurate preoperative diagnosis is necessary to avoid radical resection and morbidity in patients.

We discuss here a case of 36-year-old female who presented with abdominal pain. Her CT scan of abdomen showed borderline thickening of gallbladder wall and chronic cholecystitis however on histopathological report was suggestive of xanthogranulomatous cholecystitis.