Duodenal Ulceration in a Child with Coeliac Disease

Lototskaya, Polina S. and Manina, Marina A. and Tertychnyy, Aleksandr S. and Zamyatnin, Andrey A. and Erdes, Svetlana I. (2020) Duodenal Ulceration in a Child with Coeliac Disease. Diagnostics, 10 (1). p. 31. ISSN 2075-4418

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Abstract

Coeliac disease (CD) is a gluten-dependent inflammatory disease of the small bowel that affects up to 1% of the global population. Herein, the presence of ulcers, erosions, or strictures in the duodenum for non-advanced cases of CD is a rarity. Case report: We present a clinical case of a 17-year-old girl, who from the age of 9, had suffered from erosive Helicobacter pylori (HP)-associated gastritis and erosive duodenitis. At 16, she was diagnosed with a duodenal ulcer, complicated by cicatricial deformity of the bulb. While an atypical course in the development of the disease had led to the initial delay in diagnosis, a serum study and an intestinal biopsy confirmed CD. Discussion: A recent study found an elevated rate of peptic ulcer disease in patients with CD. From literature searches, comorbid HP infection and CD have indeed been widely reported, whereas cases highlighting the prevalence of CD-associated peptic ulcers have been observed and reported in only a few instances. Consequently, greater awareness is warranted and must be exercised for identifying the origins of ulcerative lesions that may be CD-related or -derived.

Item Type: Article
Subjects: Impact Archive > Medical Science
Depositing User: Managing Editor
Date Deposited: 27 Feb 2023 05:28
Last Modified: 29 Jul 2024 10:07
URI: http://research.sdpublishers.net/id/eprint/1530

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