Immunotherapy as a Future Treatment for Relapsed and Metastatic Primary Pulmonary Sarcomas

Primary pulmonary sarcomas (PPS) are aggressive tumors that are ideally treated with complete surgical resection, although seldom possible. Chemotherapy and radiotherapy have proven to be inadequate as second-line in the majority of cases, requiring investigation into novel approaches to treatment. Due to the high rate of recurrence and advanced disease progression, immunotherapy is a future treatment modality that must be investigated in order to provide better prognosis. Studies predominantly focus on other soft tissue malignancies such as osteosarcoma, and thus research pertaining to PPS is limited.